REVIVE NX — Exosome & Nidogen

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Indications:

Skin ageing and photoageing. Loss of elasticity and firmness. Fine and deep wrinkles (including crow’s feet). Dull, lacklustre complexion. Hyperpigmentation and melasma. Skin redness and inflammatory conditions. Dehydrated, atonic and fragile skin. Post-procedural regeneration after microneedling, laser, peels. Alopecia and scalp revitalisation.

Compound:

KEY ACTIVE INGREDIENTS:

MD-Exosomes (150 billion / vial) — 5th-generation exosomes with therapeutic action, derived from Lactobacillus paracasei (a lactic acid bacterium with powerful regenerative properties). Concentration 200X above the market standard — the highest concentration in the world. Stabilised size < 100 nm for rapid penetration and immediate release of active ingredients into the dermis.

Exosome sources:
I. Mesenchymal cells (amniotic fluid / umbilical cord)
II. Adipose tissue stem cells
III. Animal stem cells
IV. Plant stem cells

CHA-Zeromelatide (epidermis) — fundamental antioxidant and depigmenting action; reduces melanin and evens out skin tone.

CHA-Nidogen-1 (basal membrane) — restores the dermo-epidermal junction, rebuilds barrier function.

EGF — Epidermal Growth Factor: cell regeneration, stimulation of keratinocyte, endothelial cell and fibroblast proliferation.

MD-Exosomes (dermis) — deep anti-inflammatory action, restoration of cellular proliferation and collagen synthesis.

Volume:

5 ml

Manufacturer:

CHA Meditech Co., Ltd. (South Korea)

Recommended course:

STANDARD PROTOCOL (1 procedure): STEP 1 — Skin preparation: microneedling / RF-microneedling / peeling / laser procedures / needle-free system. STEP 2 — Main application: uniform topical application after procedure. • Face — 1–3 ml • Neck — 1 ml • Décolleté — 1 ml • Hands — 1 ml • Scalp — 2–5 ml Leave for 20 minutes until fully absorbed. STEP 3 — Completion: Celltermi Repair Mask (reduces hyperemia, hydrates). STEP 4 — Home care: Celltermi Peptosome Repair Cream + Celltermi Repair Mist. MAIN PROTOCOL (Vial 1 + Vial 2): Needle RF: 2 ml NX before and during procedure + 1 ml on the overlap zone. Interval: every 4 weeks. Course: 5 procedures. Bipolar RF: 5 ml NX + RF contact cream. Interval: every 1–2 months. Maintenance: every 6 months. Air Ject: dilute 3 ml with saline solution. Interval: every 5–6 months. Maintenance: every 6 months. Derma Pen: topical application of NX after Derma Pen. Interval: every 1–2 months. Course: 3 procedures. IMPORTANT: for maximum effect, micro-damage to the skin must be created, through which exosomes penetrate uniformly into the dermis.

Price:

€136.00

CELLTERMI REVIVE NX is a next-generation exosomal therapy — the world’s first 5th-generation product, acting simultaneously on all 3 key layers of the skin: epidermis, basal membrane and dermis. The product contains 150 billion MD-exosomes per vial — the highest concentration in the world, 200 times above the market standard. Exosomes are derived from Lactobacillus paracasei, with a stabilised size < 100 nm, ensuring rapid penetration and immediate release of active components. The unique formula combines three active complexes: CHA-Zeromelatide (for the epidermis), CHA-Nidogen-1 (for the basal membrane) and MD-Exosomes (for the dermis) — providing a complete solution for regeneration, rejuvenation, hydration, pigmentation reduction and inflammation control. Zero immunogenicity — no allergic reactions or inflammation. No risk of rejection. No aggression to the skin.

REVIVE NX works simultaneously on three levels: 1. EPIDERMIS — CHA-ZEROMELATIDE + EGF CHA-Zeromelatide exerts fundamental antioxidant and depigmenting action — reducing melanin content and evening out skin tone. EGF stimulates cell regeneration and the proliferation of keratinocytes, endothelial cells and fibroblasts. 2. BASAL MEMBRANE — CHA-NIDOGEN-1 Restores the dermo-epidermal junction — the connection between the epidermis and dermis. Rebuilds the skin’s barrier function and the structure of the basal membrane damaged by ageing and external factors. 3. DERMIS — MD-EXOSOMES (150 billion) 5th-generation exosomes exert deep anti-inflammatory action, restore cellular proliferation and stimulate collagen synthesis. Size < 100 nm ensures rapid penetration, immediate release and 200X more efficient delivery compared to other products.

– 150 billion MD-exosomes / vial — the highest concentration in the world – 5th-generation exosomal therapy — the first of its kind in the world – Action on 3 levels simultaneously: epidermis + basal membrane + dermis – 200X more efficient delivery of active components vs. standard – Stabilised size < 100 nm — rapid penetration and immediate release – Zero immunogenicity — no allergies, no inflammation, no rejection risk – Clinically proven: +25.21% hydration, +55.56% radiance, −39.56% crow's feet – −26.82% melanin, −85.10% pigmented area (melasma) after 4 procedures – −25.29% haemoglobin concentration, −26.22% redness after 4 procedures – +21.12% skin texture improvement after 4 procedures – Effective for face, neck, décolleté, hands and scalp – Compatible with microneedling, RF, laser, peels, Air Ject, Derma Pen – Developed in Switzerland and South Korea — pharmaceutical standards

What are the MD-exosomes in REVIVE NX?

MD-exosomes are exosomes with therapeutic action derived from Lactobacillus paracasei, with a stabilised size < 100 nm, which rapidly penetrate the deep layers of the skin and trigger regeneration processes.

Why 150 billion exosomes?

More exosomes means more delivery of active components, a higher degree of impact on damaged cells and a more powerful, targeted rejuvenation effect.

Is there a risk of allergic reactions?

No. REVIVE NX has zero immunogenicity — it causes no allergic reactions, inflammation or rejection risk.

Which procedures is it combined with?

Microneedling, RF-microneedling, laser, peels, Air Ject, Derma Pen — the product is applied topically after creating micro-damage for optimal penetration.

How many procedures are required?

Depends on the device used: 5 procedures with Needle RF (every 4 weeks) or 3 procedures with Derma Pen (every 1–2 months).

What are the clinically proven results?

+25.21% hydration, +55.56% radiance, −39.56% crow’s feet, −26.82% melanin, −85.10% pigmented area, +21.12% texture — after 4 procedures.

Can it be used on the scalp?

Yes, 2–5 ml for scalp revitalisation and alopecia treatment.